How is HbA1c testing used to predict the development of type 2 diabetes mellitus (DM) in children and adolescents?

Updated: Jul 13, 2021
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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However, a study by Vijayakumar et al suggested, in contrast, that the evaluation of HbA1c levels is as effective as FPG and 2-hour postload plasma glucose tests in predicting the development of type 2 diabetes in children and adolescents. The study determined that among the report's subjects, the incidence of diabetes at follow-up was fourfold higher in male children and adolescents belonging to the highest HbA1c category (5.7-6.4%) at baseline than in those in the lowest category (5.3% or lower), while the incidence of diabetes in female children and adolescents in the highest category was sevenfold greater than in those belonging to the lowest category. [154, 155]

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