What are the ADA diagnostic criteria for diabetes mellitus (DM)?

Updated: Oct 23, 2019
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Answer

The American Diabetes Association (ADA) criteria for the diagnosis of diabetes are any of the following [1] :

  • An HbA1c level of 6.5% or higher; the test should be performed in a laboratory using a method that is certified by the National Glycohemoglobin Standardization Program (NGSP) and standardized or traceable to the Diabetes Control and Complications Trial (DCCT) reference assay, or

  • A fasting plasma glucose (FPG) level of 126 mg/dL (7.0 mmol/L) or higher; fasting is defined as no caloric intake for at least 8 hours, or

  • A 2-hour plasma glucose level of 200 mg/dL (11.1 mmol/L) or higher during a 75-g oral glucose tolerance test (OGTT), or

  • A random plasma glucose of 200 mg/dL (11.1 mmol/L) or higher in a patient with classic symptoms of hyperglycemia (ie, polyuria, polydipsia, polyphagia, weight loss) or hyperglycemic crisis

The American Association of Clinical Endocrinologists, however, recommends that HbA1c be considered an additional optional diagnostic criterion, rather than a primary criterion for diagnosis of diabetes. [106]


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