What factors influence the prognosis of type 2 diabetes mellitus (DM)?

Updated: Sep 27, 2021
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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The prognosis in patients with diabetes mellitus is strongly influenced by the degree of control of their disease. Chronic hyperglycemia is associated with an increased risk of microvascular complications, as shown in the Diabetes Control and Complications Trial (DCCT) in individuals with type 1 diabetes [80, 81] and the United Kingdom Prospective Diabetes Study (UKPDS) in people with type 2 diabetes. [82]

Reversion to normal glucose regulation during attempts to prevent progression of pre-diabetes to frank diabetes is a good indicator of slowing disease progression, and it is associated with a better prognosis. [83]

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