How does obesity affect the risk of developing type 2 diabetes mellitus (DM)?

Updated: Jul 13, 2021
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Answer

Approximately 90% of individuals with type 2 diabetes mellitus are overweight or have obesity. [50] However, a large, population-based, prospective study has shown that an energy-dense diet may be a risk factor for the development of diabetes that is independent of baseline obesity. [51]

A study by Cameron et al indicated that in the United States between 2013 and 2016, obesity was responsible for the development of new-onset diabetes in 41% of adults. The highest attributable rate of obesity-related diabetes was among non-Hispanic White women (53%); non-Hispanic Black men demonstrated the lowest rate, with the attributable fraction being 30%. [52, 53]


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