What are the definition and prevalence of gestational diabetes mellitus (DM)?

Updated: Jul 13, 2021
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Gestational diabetes mellitus is defined as any degree of glucose intolerance with onset or first recognition during pregnancy (see Diabetes Mellitus and Pregnancy). Gestational diabetes mellitus is a complication of approximately 4% of all pregnancies in the United States. A steady decline in insulin sensitivity as gestation progresses is a normal feature of pregnancy; gestational diabetes mellitus results when maternal insulin secretion cannot increase sufficiently to counteract the decrease in insulin sensitivity.

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