How do the complications of diabetes mellitus (DM) differ by type?

Updated: Sep 27, 2021
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Although the pathophysiology of the disease differs between the types of diabetes, most of the complications, including microvascular, macrovascular, and neuropathic, are similar regardless of the type of diabetes. Hyperglycemia appears to be the determinant of microvascular and metabolic complications. Macrovascular disease may be less related to glycemia.

Telomere attrition may be a marker associated with presence and the number of diabetic complications. Whether it is a cause or a consequence of diabetes remains to be seen. [26]

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