What are the EASD-ADA treatment guidelines for type 2 diabetes mellitus (DM)?

Updated: Jul 13, 2021
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Recommendations for the treatment of type 2 diabetes mellitus from the European Association for the Study of Diabetes (EASD) and the American Diabetes Association (ADA) place the patient's condition, desires, abilities, and tolerances at the center of the decision-making process. [4, 5, 6]

The EASD/ADA position statement contains 7 key points:

  1. Individualized glycemic targets and glucose-lowering therapies

  2. Diet, exercise, and education as the foundation of the treatment program

  3. Use of metformin as the optimal first-line drug unless contraindicated

  4. After metformin, the use of 1 or 2 additional oral or injectable agents, with a goal of minimizing adverse effects if possible

  5. Ultimately, insulin therapy alone or with other agents if needed to maintain blood glucose control

  6. Where possible, all treatment decisions should involve the patient, with a focus on patient preferences, needs, and values

  7. A major focus on comprehensive cardiovascular risk reduction

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