Which medications in the drug class Water-Soluble Vitamins are used in the treatment of Childhood Migraine Variants?

Updated: Nov 19, 2019
  • Author: Wendy G Mitchell, MD; Chief Editor: Stephen L Nelson, Jr, MD, PhD, FAACPDM, FAAN, FAAP, FANA  more...
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Answer

Water-Soluble Vitamins

Riboflavin, with or without magnesium supplements and with or without herbs (eg, feverfew), has been used as prophylaxis for migraine headaches. For adults, the dosage ranges from 200-400 mg/day; no pediatric dose has been established. The only side effect is bright yellow-green discoloration of the urine. Patients should be warned about this harmless effect so that they do not become unduly alarmed.

Riboflavin (Riobi)

Riboflavin is essential in the activation of pyridoxine and the conversion of tryptophan to niacin. It is a component of flavoprotein enzymes, which are necessary for tissue respiration.


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