Which medications are used in the treatment of childhood migraine variants (equivalents)?

Updated: Nov 19, 2019
  • Author: Wendy G Mitchell, MD; Chief Editor: Stephen L Nelson, Jr, MD, PhD, FAACPDM, FAAN, FAAP, FANA  more...
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Agents used for acute abortive treatment of childhood migraine variants include the following:

  • Antiemetic or sedatives

  • Minor analgesics

  • Ergotamines

  • Triptans [23, 24]

  • Fluid replacement solutions, if vomiting is severe

Long-term prophylaxis is indicated if episodes are frequent or disruptive and if patients or families desire treatment and are ready to comply with daily medication. Agents used for this purpose include the following:

  • Beta blockers

  • Tricyclic antidepressants (TCAs)

  • Aspirin (minidose)

  • Anticonvulsants

  • Cyproheptadine

  • High-dose vitamin B-2 (riboflavin) combined with high doses of magnesium salts (usually magnesium oxide or citrate)

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