What are the age-related predilections of tuberous sclerosis complex (TSC)?

Updated: Aug 21, 2018
  • Author: David Neal Franz, MD; Chief Editor: Amy Kao, MD  more...
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Various organ systems are affected maximally at different points in life.

  • Cardiac involvement occurs during the intrauterine or neonatal period.

  • Rhabdomyomas tend to regress over time.

  • Epilepsy, autism, and developmental delays manifest themselves from infancy to adolescence.

  • Polycystic kidney disease usually is apparent in infancy or early childhood.

  • AMLs may develop at any time from childhood into adult life.

  • Lymphangiomyomatosis typically presents in the third or fourth decade of life.

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