Which patient groups have the highest risk for developing tuberous sclerosis complex (TSC)?

Updated: Aug 21, 2018
  • Author: David Neal Franz, MD; Chief Editor: Amy Kao, MD  more...
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TSC affects all races without a clear-cut predominance.

TSC affects both sexes equally. Some studies have suggested that males are more likely to suffer neurological morbidity, but this has not been demonstrated conclusively.

TSC can present at any age. In infants and children, it usually is identified as a cause of epilepsy, autism, or cardiac failure.

Older persons [9] may present with renal failure or pulmonary or cutaneous manifestations in the absence of prominent, or any, neurological symptoms.

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