What is the role of a free thyroxine assay in the workup of Sturge-Weber syndrome (SWS)?

Updated: Dec 26, 2018
  • Author: Masanori Takeoka, MD; Chief Editor: George I Jallo, MD  more...
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Answer

A study by Siddique et al indicated that in patients with SWS who are taking anticonvulsants (which can cause abnormal results on thyroid function tests), a free thyroxine equilibrium dialysis assay is a more accurate means of diagnosing true hypothyroidism than is thyroid function testing. The investigators found that out of 5 children with SWS who were taking anticonvulsants and had been diagnosed with hypothyroidism using thyroid function testing, only 2 were revealed to have true hypothyroidism when tested with a free thyroxine equilibrium dialysis assay. [58]


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