Which clinical history findings are characteristic of a progressive course of cortical injury in Sturge-Weber syndrome (SWS)?

Updated: Dec 26, 2018
  • Author: Masanori Takeoka, MD; Chief Editor: George I Jallo, MD  more...
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Answer

Factors suggesting a progressive course of cortical injury in SWS include the following:

  • Initial focal seizures progressing to frequent, secondarily generalized seizures

  • Increasing seizure frequency and duration despite the use of antiepileptic drugs (AEDs)

  • Increasing duration of a transient postictal deficit

  • Increase in focal or diffuse atrophy determined by serial neuroimaging

  • Progressive increase in calcifications

  • Development of hemiparesis

  • Deterioration in cognitive functioning


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