What are prognostic factors in Sturge-Weber syndrome (SWS)?

Updated: Dec 26, 2018
  • Author: Masanori Takeoka, MD; Chief Editor: George I Jallo, MD  more...
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Answer

Factors predicting a poor outcome (or indicating potential need for surgery) in SWS include the following:

  • Early seizure onset

  • Extensive leptomeningeal angioma (LA)

  • Medically refractive seizures

  • Relapsing or permanent motor deficits

  • Headaches or mild trauma associated with transient motor deficits

  • Evidence of progressive neurologic damage

  • Focal seizures with subsequent generalization

  • Increasing seizure frequency and duration

  • Increasing duration of postictal deficits

  • Increasing focal or diffuse atrophy

  • Progressive atrophy or calcifications

  • Development of hemiparesis

  • Deterioration in cognitive functioning (loss of intellectual abilities)


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