Which intermediate-acting insulins are used for the treatment of type 1 diabetes mellitus (DM)?

Updated: Nov 30, 2020
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
  • Print
Answer

Intermediate-acting insulins include NPH insulin, a crystalline suspension of human insulin with protamine and zinc. NPH provides a slower onset of action and longer duration of action than regular insulin does. The onset of action usually occurs at 1-2 hours, the peak effect is noted at 4-12 hours, and the duration of action is normally 14–24 hours.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!