What are complications of type 1 diabetes mellitus (DM)?

Updated: Sep 13, 2019
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Answer

The morbidity and mortality associated with diabetes are related to the short- and long-term complications. Such complications include the following:

  • Hypoglycemia from management errors

  • Increased risk of infections

  • Microvascular complications (eg, retinopathy and nephropathy)

  • Neuropathic complications

  • Macrovascular disease

These complications result in increased risk for ischemic heart disease, cerebral vascular disease, peripheral vascular disease with gangrene of lower limbs, chronic renal disease, reduced visual acuity and blindness, and autonomic and peripheral neuropathy. Diabetes is the major cause of blindness in adults aged 20-74 years, as well as the leading cause of nontraumatic lower-extremity amputation and ESRD.


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