Which DR-DQ haplotypes decrease the risk for type 1 diabetes mellitus (DM)?

Updated: Dec 01, 2020
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Answer

Other haplotypes appear to offer protection against type 1 DM. These include the following [26] :

  • DRB1*1501 - DQA1*0102 - DQB1*0602 (OR 0.03)

  • DRB1*1401 - DQA1*0101 - DQB1*0503 (OR 0.02)

  • DRB1*0701 - DQA1*0201 - DQB1*0303 (OR 0.02)


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