Which physical findings are pathognomonic for Lennox-Gastaut syndrome (LGS)?

Updated: Nov 09, 2018
  • Author: Koshi A Cherian, MD; Chief Editor: Amy Kao, MD  more...
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Findings on general physical examination are normal in many patients with LGS. There are no physical findings pathognomonic for LGS.

Nevertheless, the general physical examination can be important in helping to identify specific etiologies that have both systemic and neurologic manifestations (eg, adenoma sebaceum or ash leaf macules in tuberous sclerosis). Use a Wood lamp to examine the skin. Patients may exhibit moderately severe to severe growth delay, a nonspecific finding that is more a reflection of the underlying brain injury than of a specific epilepsy syndrome.

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