What is cryptogenic Lennox-Gastaut syndrome (LGS)?

Updated: Nov 09, 2018
  • Author: Koshi A Cherian, MD; Chief Editor: Amy Kao, MD  more...
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Answer

In addition to idiopathic and symptomatic LGS, some investigators add “cryptogenic” as a third etiologic category. [2] This category encompasses cases in which the epilepsy appears to be symptomatic but a cause cannot be identified. In an epidemiologic study in Atlanta, Georgia, 44% of patients with LGS were in the cryptogenic group. In a series of 23 patients with cryptogenic LGS, 2.5-47.8% had a family history of epilepsy and febrile seizures.


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