What types of seizures occur in Lennox-Gastaut syndrome (LGS)?

Updated: Nov 09, 2018
  • Author: Koshi A Cherian, MD; Chief Editor: Amy Kao, MD  more...
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Answer

Ictal clinical manifestations include the following:

  • Tonic seizures (frequency, 17-95%) - Can occur during wakefulness or sleep but are more frequent during non–rapid eye movement (REM) sleep; may be axial, axiorhizomelic, or global; may be asymmetric

  • Atypical absence seizures (frequency, 17-100%) – Can have gradual onset, with incomplete loss of consciousness; associated eyelid myoclonias may be noted

  • Atonic, massive myoclonic, and myoclonic-atonic seizures (frequency, 10-56%) – Can all cause a sudden fall, producing injuries, or may be limited to the head falling on the chest; pure atonic seizures are exceptional

  • Other types of seizures (generalized tonic-clonic [15%], complex partial [5%], absence status epilepticus, tonic status epilepticus, nonconvulsive status epilepticus)


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