Which medications in the drug class Diuretics, Thiazide are used in the treatment of Diabetes Insipidus?

Updated: Mar 18, 2020
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Diuretics, Thiazide

Diuretics may reduce flow to the ADH-sensitive distal nephron.

Hydrochlorothiazide (Microzide)

Hydrochlorothiazide is a thiazide diuretic that decreases urinary volume in the absence of ADH. It may induce mild volume depletion and cause proximal salt and water retention, thereby reducing flow to the ADH-sensitive distal nephron. Its effects are additive to those of other agents.

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