What is the most sensitive indicator of water balance in diabetes insipidus (DI)?

Updated: Mar 18, 2020
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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In mentally intact patients, thirst is the most sensitive indicator of water balance. Many patients have a predilection for drinking cold liquids, often water. Neurologic symptoms vary with the patient’s access to water; patients with free access may have no neurologic symptoms at all. However, the clinical presentation depends on the cause and severity, as well as on the patient’s associated medical condition(s).

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