How is central diabetes insipidus (DI) characterized?

Updated: Mar 18, 2020
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Answer

Central DI is characterized by decreased secretion of antidiuretic hormone (ADH)—also known as arginine vasopressin (AVP)—which gives rise to polyuria and polydipsia by diminishing the person’s ability to concentrate urine. Other terms for central DI are neurogenic, pituitary, and neurohypophyseal DI. (See Etiology, Presentation, and Workup.)


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