What is the role of imaging studies in the workup of infantile spasm (West syndrome)?

Updated: Jan 11, 2019
  • Author: Tracy A Glauser, MD; Chief Editor: Stephen L Nelson, Jr, MD, PhD, FAACPDM, FAAN, FAAP  more...
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Answer

About 70-80% of patients have abnormal findings on neuroimaging studies. Magnetic resonance imaging (MRI) of the brain provides a more detailed evaluation than does computed tomography (CT) scanning of the brain. Imaging studies should be obtained prior to starting ACTH or steroid therapy, as these therapies are associated with the appearance of apparent brain atrophy as treatment continues.


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