What is the role of lumbar puncture in the workup of infantile spasm (West syndrome)?

Updated: Jan 11, 2019
  • Author: Tracy A Glauser, MD; Chief Editor: Stephen L Nelson, Jr, MD, PhD, FAACPDM, FAAN, FAAP  more...
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Answer

In young infants with early onset of infantile spasms, consider a lumbar puncture as part of a full sepsis workup to look for signs of meningitis.

In older infants in whom no clear signs of infection are present, a lumbar puncture is useful in evaluating metabolic causes of infantile spasms, such as nonketotic hyperglycinemia.


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