What are the favorable prognostic factors of infantile spasm (West syndrome)?

Updated: Jan 11, 2019
  • Author: Tracy A Glauser, MD; Chief Editor: Stephen L Nelson, Jr, MD, PhD, FAACPDM, FAAN, FAAP  more...
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Answer

Favorable prognostic factors also include the following:

  • Cryptogenic or idiopathic etiology

  • Age of onset of over 4 months

  • Absence of atypical spasms and partial seizures

  • Absence of asymmetrical EEG abnormalities

  • Short time from onset to treatment

  • Early, sustained response to treatment

Infants with symptomatic infantile spasms have been shown to be at higher risk for the development of autism spectrum disorders, compared with those infants with cryptogenic or idiopathic spasms. [10, 11]


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