Which medications are used in the treatment of mercury toxicity?

Updated: Nov 05, 2018
  • Author: David A Olson, MD; Chief Editor: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS  more...
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Answer

As previously discussed, 2,3-dimercaptosuccinic acid (DMSA) and N -acetyl-D,L-penicillamine have been used as chelating agents in the treatment of mercury toxicity. Use chelating agents if the patient is symptomatic, systemic absorption is anticipated, or increased blood or urine levels are present. Chelating agents should be administered early in treatment.

GI decontamination may be useful only in acute, recent ingestions. Activated charcoal is indicated for GI decontamination because it binds inorganic and organic mercury compounds to some extent.


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