What causes apoptosis in the pathophysiology of mercury toxicity?

Updated: Nov 05, 2018
  • Author: David A Olson, MD; Chief Editor: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS  more...
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Answer

Methylmercury also inactivates sodium-potassium adenosine triphosphatase (Na+/K+-ATPase), which leads to membrane depolarization, calcium entry, and eventual cell death. [12] Several pathways may be simultaneously activated converging in apoptosis. [13]


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