What are the complications of mercury toxicity in Minamata disease?

Updated: Nov 05, 2018
  • Author: David A Olson, MD; Chief Editor: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS  more...
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Minamata disease has devastating neurologic consequences as a primary outcome of methyl mercury intoxication; unfortunately, these are relatively resistant to treatment. Complications include the following (see Presentation):

  • Acute perioral and facial paresthesias

  • Visual-field constriction

  • Respiratory distress and nonspecific dermatitis

  • Extremity numbness eventually appears, along with headache, fatigue, and tremor

  • Ataxia and dysarthria can also be observed

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