What is the role of respiratory testing in the workup of sporadic inclusion body myositis (s-IBM)?

Updated: Jun 08, 2018
  • Author: Michael P Collins, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Answer

Investigators in one study suggested that respiratory function testing, including sleep study, be performed routinely in patients with s-IBM because they found that in 16 patients with biopsy proven IBM, asymptomatic impairment of respiratory function was common and sleep-disordered breathing was present in all patients tested. Four patients reported excessive daytime sleepiness; 8 had at least mild dysphagia; forced vital capacity was < 80% predicted normal in 7; sniff nasal inspiratory pressure was reduced in 3; daytime hypoxemia was present in 9; and hypercapnia was present in 1. Sleep study was performed in 15 and revealed sleep disordered breathing in all. [90]


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