Which medications in the drug class Immune modulators are used in the treatment of Stiff Person Syndrome?

Updated: Jun 14, 2018
  • Author: Nancy Theresa Rodgers-Neame, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Immune modulators

These agents alter immune response to antigens. IVIG can be used.

Immune globulin intravenous (Bivigam, Gammagard, Gamunex-C, Octagam)

Neutralizes circulating antibodies through anti-idiotypic antibodies. Down-regulates proinflammatory cytokines, including INF-gamma; blocks Fc receptors on macrophages; suppresses inducer T and B cells and augments suppressor T cells; blocks complement cascade; promotes remyelination; may increase CSF IgG (10%).

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