How is pain managed in stiff person syndrome?

Updated: Jun 14, 2018
  • Author: Nancy Theresa Rodgers-Neame, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Pain management

  • Muscle pain is often a problem with patients and can cause worsening of the spasms and a cycle of spasms, pain, more spasms, and more pain.

  • Nonsteroidal anti-inflammatory medications can be used for less severe cases.

  • Long-term therapy with amitriptyline or similar tricyclics may be helpful. Time-release opiates may also be of benefit.

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