Which lab studies are performed in the workup of stiff person syndrome?

Updated: Jun 14, 2018
  • Author: Nancy Theresa Rodgers-Neame, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Answer

Obtain the following laboratory tests and interpret the results as outlined in Pathophysiology:

  • Hemoglobin A1C: This is obtained because of association with diabetes mellitus.

  • Complete blood count: An association with pernicious anemia has been reported.

  • Comprehensive metabolic profile

  • Thyroid-stimulating hormone: Thyroiditis is sometimes associated.

Special tests include the following:

  • Anti-GAD antibodies

  • Anti–pancreatic islet cell antibodies

  • Anti-amphiphysin antibodies


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