Which electrodiagnostic studies are performed in the evaluation of myasthenia gravis (MG)?

Updated: Aug 27, 2018
  • Author: Abbas Jowkar, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Answer

The following 2 studies are commonly performed:

  • Repetitive stimulation of a muscle at 2-3 Hz, also known as repetitive nerve stimulation (RNS)

  • Single-fiber electromyography (SFEMG), aimed at evaluating neuromuscular block, jitter, and fiber density

SFEMG is more sensitive than RNS in assessing MG. However, SFEMG is technically more difficult and much more dependent on the experience and skill of the testing physician. Consequently, RNS is the most frequently performed neurophysiologic test of neuromuscular transmission.


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