What is the significance of finding blocking anti-acetylcholine receptor (AChR) ab in the evaluation of myasthenia gravis (MG)?

Updated: Aug 27, 2018
  • Author: Abbas Jowkar, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Answer

These are present in approximately half of the patients with generalized MG but only 30% of patients with ocular disease. Less than 1% of MG patients have anti-AChR-ab (blocking) without detectable binding or modulating antibodies, thus, this test not clinically useful. [44]


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