Which lab test is used to determine severity of myasthenia gravis (MG)?

Updated: Aug 27, 2018
  • Author: Abbas Jowkar, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Answer

The serum titer of the acetyl-choline receptor antibodies does not correlate with disease severity. Their value is mainly in the initial diagnosis, or in the case of modulating antibodies as a potential marker for thymoma. Unlike anti-AChR-abs, there appears to be a correlation between anti-MuSK titers, disease severity, and the application of immunomodulatory therapy. [41]


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