What is the morbidity and mortality associated with limb-girdle muscular dystrophy (LGMD)

Updated: Aug 15, 2019
  • Author: Monica Saini, MD, MBBS, MRCP(UK); Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Answer

Morbidity and mortality rates vary. In general, early onset forms tend to have a rapid course.

Patients with severe forms may become wheelchair bound in their early teens and die from respiratory complications in their late teens.

Patients with slowly progressive LGMD may retain independent ambulation into middle age. Some patients with confirmed mutations have had nearly normal strength.


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