What is the role of edrophonium (Tensilon) testing in the workup of Lambert-Eaton myasthenic syndrome (LEMS)?

Updated: May 23, 2019
  • Author: David E Stickler, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Testing with edrophonium (Tensilon) may be performed to help differentiate LEMS from MG. However, such testing is highly subjective, and it is of little value in the diagnosis of LEMS in the ED.

The test may produce an improvement in strength, but rarely is the response in patients with LEMS as noticeable as the typical response in patients with MG.

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