What is the role of ACh receptor antibody testing in the workup of Lambert-Eaton myasthenic syndrome (LEMS)?

Updated: May 23, 2019
  • Author: David E Stickler, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Answer

ACh receptor (AChR) antibodies are most commonly associated with myasthenia gravis (MG) and are occasionally found in low titers in LEMS. The only true methods of differentiating MG from LEMS are the detection of AChR antibodies and the presence of underlying malignancy.


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