What are the approach considerations in the workup of Lambert-Eaton myasthenic syndrome (LEMS)?

Updated: May 23, 2019
  • Author: David E Stickler, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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In the emergency setting, very few tests are of importance in regard to Lambert-Eaton myasthenic syndrome (LEMS), because the diagnosis is not made in the emergency department (ED). It would be reasonable, however, to consider basic tests in any patient with cancer who reports weakness and dry mouth. These basic tests would include the following:

  • Complete blood count

  • Basic chemistry

  • Pulse oximetry

Other, more specific tests are ordered as indicated (see below).

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