What are other symptoms of Lambert-Eaton myasthenic syndrome (LEMS)?

Updated: May 23, 2019
  • Author: David E Stickler, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Answer

Most patients have a dry mouth, which frequently precedes other symptoms of LEMS. (Many do not mention this unless specifically questioned.) Many patients report an unpleasant metallic taste. Some patients have other manifestations of autonomic dysfunction, including impotence in males and postural hypotension.

LEMS may be discovered first when prolonged paralysis follows the use of neuromuscular blocking agents during surgery.

Exacerbation of weakness has been described after administration of aminoglycoside or fluoroquinolone antibiotics, magnesium, calcium channel blockers, and iodinated intravenous contrast agents.


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