What is the role of injection myopathy in the etiology of focal muscular atrophy (FMA)?

Updated: Feb 20, 2018
  • Author: Sridharan Ramaratnam, MD, MBBS; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

Injection myopathy [47]

  • Deltoid and/or gluteal fibrotic contractures are seen in some patients who receive repeated intragluteal or intradeltoid injections.

  • FMA and weakness of the involved muscles result.

  • Nearly one third of the patient's siblings may be affected by the same fibromuscular disorder.

  • EMG reveals myopathic changes in the affected muscles.

  • Repeated injection injuries and myotoxicity, resulting in multifocal myositis and abnormal control of collagen formation, could be important pathogenic factors.


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