What is the role of immune-mediated syndromes in the etiology of focal muscular atrophy (FMA)?

Updated: Feb 20, 2018
  • Author: Sridharan Ramaratnam, MD, MBBS; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

Immune-mediated syndromes that mimic ALS

  • Serum monoclonal gammopathy is encountered more frequently among patients with motor neuron disease than in neurologic disease control patients.

  • The frequency of LMN disease that resembles progressive muscular atrophy is more common in these patients than in motor neuron disease that is unassociated with gammopathy.


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