What is the role of multifocal motor neuropathy in the etiology of focal muscular atrophy (FMA)?

Updated: Feb 20, 2018
  • Author: Sridharan Ramaratnam, MD, MBBS; Chief Editor: Helmi L Lutsep, MD  more...
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Multifocal motor neuropathy with conduction block and high-titer serum anti-GM1 antibodies

  • This motor syndrome is more common in males.

  • This disorder typically is associated with atrophic hand weakness. No bulbar or upper motor neuron (UMN) signs are noted. Conduction block in motor nerves and high serum titers of anti-GM1 antibodies are present.

  • Multifocal motor neuropathy also may occur without elevation of anti-GM1 antibody titers.

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