Which medications in the drug class Antidepressant, Selective Serotonin/norepinephrine Reuptake Inhibitor (SSNRI) are used in the treatment of Diabetic Neuropathy?

Updated: Jan 17, 2020
  • Author: Dianna Quan, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

Antidepressant, Selective Serotonin/norepinephrine Reuptake Inhibitor (SSNRI)

Duloxetine (Cymbalta) was the first medication to be approved specifically for the treatment of diabetic neuropathy. Venlafaxine (Effexor) has been recommended by the AAN/AANEM/AAPMR guidelines for consideration in diabetic neuropathy pain management. [112]

Duloxetine (Cymbalta, Drizalma Sprinkle)

Indicated for diabetic peripheral neuropathic pain. Potent inhibitor of neuronal serotonin and norepinephrine reuptake.


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