Which medications are used in the treatment of diabetic neuropathy?

Updated: Jan 17, 2020
  • Author: Dianna Quan, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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For the treatment of diabetic neuropathy, acute cases may be able to be managed with standard analgesics, but other agents will likely be necessary for chronic pain. Occasionally, muscle relaxants may be of benefit in the first 2 weeks of therapy.

Each type of pain or a combination of pain types should be treated. Reevaluation of the painful neuropathy should be performed every 6 weeks. [104] Every effort should be made to taper and eventually to stop therapies. Therapies may need to be reinstated at later dates if symptoms flare up.

The pharmacologic agents listed below are commonly used for the symptomatic treatment of diabetic neuropathy. Most are not specifically approved by the United States Food and Drug Administration for this use, however. [18, 86, 88, 89, 73, 27, 20, 105, 106, 107]

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