Which tests are used to exclude common causes of neuropathy other than diabetes?

Updated: Jan 17, 2020
  • Author: Dianna Quan, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Testing is tailored depending on the clinical presentation. Examples of tests suggested as basic screening tools to exclude common causes of neuropathy other than diabetes include the following:

  • Complete blood cell count

  • Complete metabolic panel (electrolytes and liver function panel)

  • Vitamin B-12 and folate levels

  • Thyroid function tests

  • Erythrocyte sedimentation rate

  • C-reactive protein

  • Serum protein electrophoresis with immunofixation electrophoresis

  • Antinuclear antibody

  • Anti-SSA and SSB antibodies

  • Rheumatoid factor

  • Paraneoplastic antibodies

  • Rapid plasma reagin

  • Genetic screens

  • Hematology screen to check for anemia

  • Sequential multiple analysis-7 (SMA7) to check renal function and electrolyte imbalances/complete metabolic panel (CMP)

For more information, see Type 2 Diabetes and TCF7L2.

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