What is the progression of symptoms for chronic symmetrical diabetic neuropathy?

Updated: Jan 08, 2019
  • Author: Dianna Quan, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

When sensory symptoms ascend above the knees, similar symptoms develop in the hands, progressing proximally in a glove-like distribution. At a very late stage, the anterior aspect of the trunk and vertex of the head may be affected. The loss of sensation in the feet predisposes to development of foot ulcers and gangrene. [58] In addition, mild weakness of foot muscles and decreased ankle and knee reflexes occur commonly. With impaired proprioception and vibratory perception, gait may be affected (sensory ataxia).


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