What is chronic symmetrical diabetic neuropathy?

Updated: Jan 17, 2020
  • Author: Dianna Quan, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Distal symmetrical sensorimotor polyneuropathy affects sensory, motor, and autonomic functions in varying degrees, with sensory abnormalities predominating. Chronic symmetrical symptoms affect peripheral nerves in a length-dependent pattern, with the longest nerves affected first. Patients commonly present with painful paresthesias and numbness, which begin in the toes and ascend proximally in a stocking-like distribution over months and years.

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