Which histologic findings are characteristic of HIV-associated multiple mononeuropathies?

Updated: Oct 23, 2019
  • Author: Emad R Noor, MBChB; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Answer

Answer

Histologic findings show axonal degeneration with perivascular mononuclear infiltrates. Occasionally, the infiltrate is predominantly polymorphonuclear.

In patients with multiple mononeuropathies due to CMV infection, CMV inclusions can be seen in mononuclear and endothelial cells, and CMV can be identified by culture or polymerase chain reaction. Occasionally, a prominent necrotizing arteritis can be seen.


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